Methylglyoxal-induced Superoxide Anion Production in Endothelial Cells
نویسندگان
چکیده
منابع مشابه
Hypercholesterolemia increases endothelial superoxide anion production.
Indirect evidence suggests accelerated degradation of endothelium-derived nitric oxide (ENDO) by superoxide anion (O2-) in hypercholesterolemic vessels (HV). To directly measure O2- production by normal vessels (NV) and HV, we used an assay for O2- based on the chemiluminescence (CL) of lucigenin (L). HV (1 mo cholesterol-fed rabbits) produced threefold more O2- than NV (1.47 +/- 0.20 nM/mg tis...
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ژورنال
عنوان ژورنال: YAKUGAKU ZASSHI
سال: 2009
ISSN: 0031-6903,1347-5231
DOI: 10.1248/yakushi.129.147